Constructing Bioartificial Organs - Unmet Clinical Needs to Engage Mathematical Scientists

The severe shortage of donor organs for transplant is a major limitation in the treatment of end stage organ failure. A bio-hybrid approach offers a promising pathway to alleviating the burden of organ shortage, but it will require solutions to interdisciplinary challenges that have plagued the advancement of regenerative medicine. Examples of promising avenues that will treat kidney failure, diabetes, and COPD will be presented and highlight opportunities for collaboration between engineering, clinical, and mathematical scientists.